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Disrupting the Infection Chain
Eight expert recommendations for lowering the risk of hospital-associated infection
Each year, an estimated two million patients obtain an infection that is associated with a hospital visit, according to the Centers for Disease Control and Prevention (CDC). About 90,000 of those end in death. Hospital-acquired infections kill more people each year than breast cancer (40,870), prostate cancer (30,350), and AIDS (15,798), reports the American Public Health Association (APHA). These infections result in millions of excess hospital days—often taking critically needed intensive care unit beds—and cost the health care system more than $5 billion annually.
Interestingly, most health care-associated infections are caused by multidrug-resistant organisms, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), according to APHA. And most of these infections can be prevented by employing basic infection prevention and control methods.
Infection control is such a serious matter that, in October 2006, the CDC issued new guidelines that prescribe strategies to prevent the spread of drug-resistant infections in health care settings. Released as Management of Multidrug-Resistant Organisms in Healthcare Settings, the guidance is designed to cause hospital leaders to place greater emphasis on maintaining an effective infection control program, according to CDC spokesperson Jennifer Morcone.
The guidelines, along with an increasing industry-wide focus on infection control, will help environmental services staff receive greater respect from other departments, says Judene Bartley, CIC, in the December 2006 Health Facilities Management article entitled “Breaking the Chain” by Steve Davis. Bartley is the vice president of Beverly Hills, Mich.-based Epidemiology Consulting Services Inc. She also is a member of the Communications Task Force for the Association for Professionals in Infection Control and Epidemiology.
According to Bartley, contaminated surfaces in a health care setting increase the risk of transferring infections. And this makes environmental services staff an important line of defense in the battle to control infections.
CDC also releasing disinfection and sterilization guidances As another step to help minimize hospital-connected infections, the CDC is releasing its Guideline for Disinfection and Sterilization in Health Care Settings early this year. The guidance—expected to be more than 100 pages long—will be published in the CDC’s Morbidity Mortality Weekly Report.
The new guidelines will increase awareness of optimal disinfection and sterilization measures. However, they probably won’t lead to changes in the procedures of environmental services (ES) staff because much of the focus is on medical instruments and devices, according to Lynne Sehulster, Ph.D, a microbiologist in the CDC’s Epidemiology & Laboratory Branch. Previous guidelines that pertain to cleaning, disinfecting, medical waste and laundry are more comprehensive and, thereby, more pertinent for hospital ES departments, Sehulster adds.
The forthcoming guidelines have already been sanctioned by the CDC Hospital Infection Control Practices Advisory Committee (HICPAC). The HICPAC, which is a federal advisory committee comprised of more than a dozen external infection control experts, advises the CDC and the secretary of the Department of Health & Human Services regarding health care infection control, strategies for surveillance and prevention and control of health care-related infections.
The threat of C. difficile A major hospital infection risk is Clostridium difficile (C. difficile). This bacterium has been a concern in health care settings for more than two decades. However, it recently received greater attention because of a new strain that is stronger and more resistant to fluorquinolone antibiotics.
The emergent strain of the bacterium produces 16 times more toxin A and 23 times more toxin B than previously-identified strains of C. difficile, according to Sehulster. “In the late ’70s and early ’80s, [C. difficile] was the emerging pathogen of the day, the ‘new kid on the block,’ as it were,” Sehulster states in the Health Facilities Management piece. “All fingers now point to prior antibiotic use—primarily broad-spectrum antimicrobial agents—as the main risk factor associated with susceptibility for C. difficile-associated disease.”
Antibiotics are a major risk factor because they can reduce the level of natural beneficial bacteria within the intestines. This, in turn, can produce an environment where strains of C. difficile can thrive. If C. difficile bacteria are consumed by a patient whose normal intestinal flora are disturbed, the resulting infection can produce symptoms ranging from watery diarrhea and cramping to more serious pseudomembranous colitis and fulminant colitis, Sehulster explains.
Normally, C. difficile is in a dormant state when it’s inside the intestine. Once it is expelled along with fecal material and exposed to air, C. difficile converts into a spore and can be hard to eliminate from the environment.
According to Sehulster, there are five links in the infection chain: (1) an active pathogen sufficiently virulent to cause infection; (2) a mode of transmission for the pathogen to reach the patient; (3) quantities large enough to cause infection; (4) a susceptible host; and (5) the correct portal of entry (e.g., an open cut, mouth or eyes). “Break any of these links, and infection will not take place,” Sehulster says.
Eight strategies Sehulster and other experts have a number of environmental management strategies for lowering the risk of hospital-associated infection. Here are eight of their recommendations:
- Focus on high-touch areas — ES departments should clean rooms as frequently as possible. They should focus particularly on high-touch areas such as doorknobs, bed rails, light switches, call buttons, bed trays and bathrooms, according to Mark Regna, a technical advisor of ASHES and director of health care service with Dallas-based Jani-King International Inc. “As soil loads build up on surfaces, disinfectants have to work harder,” he says. “The more often you clean, the less there is to clean, but you have to determine what is economically feasible.”
- Prioritize technique over chemicals — ES directors should focus on the cleaning technique used by their staff, rather than the type of disinfectant being employed. “If you simply have a cloth that’s sufficiently wet and has good contact with the surface, it can make a huge difference,” Bartley says.
- Adhere to product instructions — The Environmental Protection Agency (EPA) requires disinfectant manufacturers to spell out the appropriate methods for using their products, as well as the strengths at which the chemicals are most effective. There’s a misconception that a stronger concentration of a chemical makes it more effective, Sehulster says. “If the label requires the product to be diluted, there’s a reason,” she adds. “Deviations can throw off the ionic balance.”
- Weigh the risks of using sporicides — Surface disinfectants used in hospitals generally don’t work against C. difficile spores. Chemicals such as gluteraldehyde are effective sporicides, but they can only be used on open surfaces because the vapors can be harmful. A mixture that contains sodium hypochlorite (bleach) might have some sporicidal properties, but it may not be strong enough to completely destroy the spores, she adds.
- Identify how chemicals can impact patients, staff and the environment — ES directors should choose only the most effective cleaning and disinfection products, Sehulster says. At the same time, they must consider the amount of wear and tear those products will have on the surfaces being cleaned. Bleach-based solutions, for example, can be corrosive to certain metals.
- Create multidisciplinary teams — Hospitals should create multidisciplinary teams to zero in on infection risks, recommends Sehulster. Clinical staff, for example, need to know how dust from a construction project travels through a health care facility’s ventilation system or be aware of the safety issues related to cleaners and disinfectants. Likewise, ES directors should receive training in chemistry, infection control, industrial hygiene and materials science.
- Check each other’s work — Checklists should be created by environmental services departments to detail the steps involved in cleaning a room. Then staff can use these lists to ensure all of the steps were followed, Bartley says. However, such a strategy can be difficult to follow because of the pressures on ES staff to turn rooms around quickly, Bartley admits.
- Underscore the benefits of hand washing — ES managers should emphasize the critical nature of personal hygiene among staff and patients. Hand washing among staff can help to minimize microbial contamination on frequently touched surfaces. “Microorganisms don’t travel from point A to point B by themselves. They tend to be moved by the air, by people touching surfaces or by people exposed to coughs and sneezes, Sehulster says. Hospitals should also make visitors aware of infection and urge them to wash their hands, Regna says. Staff can also post signs in patient rooms to communicate the link between hand washing and infection. “We tell doctors and nurses to wash their hands and to clean their stethoscopes before touching a patient,” Regna says, “but we need help from the patient to tell their visitors to wash their hands.”
The fight against hospital-associated infections is a top priority at facilities. And, increasingly, ES managers are becoming recognized for their crucial role in this struggle. The recommendations discussed in this article will help them expand this role, as well as improve patient health.
This article was reproduced for educational purposes from the December 2006 Health Facilities Management Magazine article entitled “Breaking the Chain” by Steve Davis. A Washington, D.C.-based freelance writer, Davis is a regular Health Facilities Management magazine contributor with extensive health care industry experience.
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